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📊 Resource Allocation by Research Phase:

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🧪 Experimental Design

🔬 Clinical Trials

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Trial Search

Current Search Criteria:

Intervention: TMC435 150 mg (Treatment A)

Found 49 matching trials

A Study to Examine Patient Characteristics, Health Care Management and Health Outcomes of Hepatitis C Virus (HCV) Patients Treated With Simeprevir

N/A

The purpose of this study is to evaluate the effectiveness of a simeprevir-...

Status

Completed

Location

Multiple Locations

Start Date

2014-02

Trial ID

NCT02103699

Treatments Being Tested

No intervention

Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Participants With Chronic Hepatitis C Virus Infection Without Cirrhosis

PHASE3

The purpose of the study is to evaluate the efficacy and safety of a treatm...

Status

Completed

Location

Multiple Locations

Start Date

2014-04

Trial ID

NCT02114177

Treatments Being Tested

Simeprevir Simeprevir Sofosbuvir Sofosbuvir

TMC647055HPC1001 - First-in-human Trial to Examine Safety, Tolerability and Pharmacokinetics (How the Drug is Absorbed Into the Bloodstream) of Increasing Single Oral Doses and of Increasing Repeated Oral Doses of TMC647055 in Healthy Volunteers and in Hepatitis C Virus Infected Patients

PHASE1

The purpose of this study is to assess the safety and tolerability of TMC64...

Status

Completed

Location

Multiple Locations

Start Date

2010-04

Trial ID

NCT01202825

Treatments Being Tested

TMC647055 Placebo TMC647055 TMC647055 Placebo TMC435 Placebo TMC647055 Placebo TMC647055

Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Subjects With Chronic Genotype 4 Hepatitis C Virus Infection

PHASE3

The purpose of this study is to show superiority of simeprevir (SMV) in com...

Status

Completed

Location

Multiple Locations

Start Date

2015-01

Trial ID

NCT02250807

Treatments Being Tested

Simeprevir Sofosbuvir

Sofosbuvir With Ribavirin or Simeprevir With HCV GT4 Egyptian Patients

PHASE2

A total of 201 participants with chronic HCV GT4 infection were allocated i...

Status

Completed

Location

Multiple Locations

Start Date

2015-04

Trial ID

NCT04385407

Treatments Being Tested

Sofosbuvir + Simeprevir + Ribavirin

A Study of the Safety and Effectiveness of Simeprevir and Sofosbuvir for Patients With HIV and Hepatitis C

PHASE4

This is a study of the safety and effectiveness of the hepatitis C medicati...

Status

Withdrawn

Location

San Francisco General Hospital, University of California, San Francisco

Start Date

2014-08

Trial ID

NCT02206932

Treatments Being Tested

Sofosbuvir + Simeprevir

A Study to Assess the Safety, Tolerability and Efficacy of TMC435 Along With Pegylated Interferon Alpha-2a (Pegasys) and Ribavirin (Copegus) Triple Therapy in Chronic Hepatitis C Genotype-1 Infected Patients Co-infected With Human Immunodeficiency Virus-Type 1

PHASE3

The purpose of this study is to evaluate the safety and tolerability of TMC...

Status

Completed

Location

Multiple Locations

Start Date

2011-10

Trial ID

NCT01479868

Treatments Being Tested

TMC435 Pegylated interferon alpha-2a Ribavirin

Early Treatment of Recurrent HCV- Infection Post Liver Transplantation in the Era of DAAs

PHASE4

The study aimed to present our experience in treating recurrent HCV genotyp...

Status

Completed

Location

Multiple Locations

Start Date

2014-09

Trial ID

NCT03133065

Treatments Being Tested

treatment of HCV with oral direct acting antiviral therapy

A Study to Evaluate the Safety, Tolerability, and Effectiveness of a 12-Week Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Patients Infected With Chronic Genotype 1 Hepatitis C Virus

PHASE2

The purpose of this study is to explore the efficacy and safety of TMC64705...

Status

Completed

Location

Multiple Locations

Start Date

2012-10

Trial ID

NCT01724086

Treatments Being Tested

TMC647055 TMC435 Ritonavir Ribavirin Pegylated interferon alpha-2a (PegIFN)GSK2336805

Study to Evaluate Drug-Drug Interaction Between IDX719 and Simeprevir in Healthy Participants (MK-1894-004)

PHASE1

The purpose of this 3-part study is to evaluate the potential impact of sim...

Status

Completed

Location

Multiple Locations

Start Date

2013-01

Trial ID

NCT01813513

Treatments Being Tested

IDX719 Simeprevir

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